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Research Highlights  

Microsurgery in an insect reveals flexibility of limb motor control

Scientists at the Universities of Leicester and Cambridge have carried out microsurgery on the legs of locusts to investigate the role of internal sense organs in the control of limb movements. Drs Keri Page and Tom Matheson artificially shortened the tendon of a leg joint receptor and then measured the animals’ ability to make aimed leg movements. The surgery led to an immediate systematic error in the movements but, remarkably, after a week’s recovery the accuracy returned to normal. This indicates that there is compensation for the erroneous sensory signal and reflects considerable plasticity in the control system for leg movements. The work is an important step forward in understanding how sensory signals are used to guide actions.

The photograph shows a surgically shortened tendon from an insect sensory receptor (the femoro-tibial chordotonal organ). This sense organ signals the position and movements of the ‘knee’ joint. Working under a microscope the tendon was cut using microsurgical scissors, then the ends were overlapped and reattached using tissue glue so that the overall tendon length was reduced. This causes the receptor to signal an incorrect knee angle. The scale bar is one tenth of a millimetre. Photo credit: K Page.

Links:

Original source article.

Dr Tom Matheson

This work was published in the Journal of Neuroscience and was funded by the BBSRC.

   

New Breakthrough in Global Warming Plant Production

Researchers one step closer to ‘Holy Grail’ of plant biology research

Researchers at the universities of Leicester and Oxford have made a discovery about plant growth which could potentially have an enormous impact on crop production as global warming increases.

Dr Kerry Franklin, from the University of Leicester Department of Biology led the study which has identified a single gene responsible for controlling plant growth responses to elevated temperature.

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Arabidopsis thaliana plants grown at 22oC (left) and 28oC (right). (Credit: Dr. Kerry Franklin, University of Leicester)

Links:

Dr Kerry Franklin

The work has been published in Current Biology (10 March 2009) and was funded by the Royal Society and the BBSRC.

   

Plant biologists discover gene that switches on 'essence of male'

Study identifies role of gene responsible for plant sperm production

Biologists at the University of Leicester have published results of a new study into plant sex – and discovered that a particular gene switches on 'the essence of male'. The study takes to a new level understanding of the genes needed for successful plant reproduction and seed production.

Professor David Twell and colleagues in the Department of Biology at the University of Leicester report a dual role for DUO1, a regulatory gene required for plant sperm cell production and show that the DUO1 gene is required to promote the division of sperm precursor cells, while at the same time promoting their specialised function as sperm cells. “It effectively switches on the essence of male”.

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Their study is reported in the journal Public Library of Science Genetics (PLoS Genetics) and was funded by the Biotechnology and Biological Sciences Research Council (BBSRC).

link to the article - click here

pollen grain

Caption: Pictured is a confocal image of an Arabidopsis pollen grain showing ectopic GFP expression in the pollen vegetative cell (outlined in red with large single green nucleus) under control of the normally male germ cell-specific histone H3 (MGH3) promoter (pair of green sperm cell nuclei). The MGH3 promoter is induced by the ectopic expression of the germline-specific transcription factor DUO1 in the pollen vegetative cell. The authors show that germ cell mitosis and specification are regulated by DUO1, including the expression of cell cycle and gamete fusion proteins. Thus DUO1 has a key integrative role linking germ cell division and sperm cell differentiation in flowering plants.

Credit: Image generated by Lynette Brownfield (University of Leicester)

Links:

Professor Dave Twell

Twell lab home page


Bumblebee colonies which are fast learners are also better able to fight off infection, according to scientists from Queen Mary, University of London and the University of Leicester. Dr Nigel Raine from Queen Mary’s School of Biological and Chemical Sciences, and Akram Alghamdi, Ezio Rosato and Eamonn Mallon from the University of Leicester tested the learning performance and immune responses of bumblebees from twelve colonies.

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or here

A bumble bee collects pollen from a flower in a garden near York, northern England, June 28, 2008.(REUTERS/Nigel Roddis)

Links:

Eamonn Mallon

Nigel Raine

     

Biologists discover gene behind ‘plant sex mystery’
An enigma – unique to flowering plants – has been solved by researchers from the University of Leicester (UK) and POSTECH, South Korea.
The discovery is reported in the journal Nature on 23 October 2008. Professor David Twell, of the Department of Biology at the University of Leicester and Professor Hong Gil Nam of POSTECH, South Korea report the discovery of a gene that has a critical role in allowing precursor reproductive cells to divide to form twin sperm cells.

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Two pollen grains viewed by fluorescence microscopy. A pair of red sperm cells are visible in the normal pollen grain (top left) whilst only one red germ cell is present in mutant pollen. (Credit: Lynette Brownfield and David Twell, University of Leicester)

Links:

Professor Dave Twell

Twell lab home page

     

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Last updated: April 2009
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